Toronto, ON – July 30, 2024 - PharmAla Biotech Holdings Inc. (“PharmAla” or the “Company”) (CSE: MDMA) (OTC:MDXXF), a biotechnology company focused on the research, development, and manufacturing of LaNeo™ MDMA and novel derivatives of MDMA (MDXX class molecules), is pleased to share its Q3 Financial Statement. The 9 months ended May 31st, 2024, included significant revenue growth compared to the previous year.
“I am pleased to report that, as compared to the same period in 2023, PharmAla has generated approximately 10x more revenue in 2024,” said Nicholas Kadysh, CEO, PharmAla Biotech. “This speaks to our success in generating new opportunities in Canada, Australia, and other ex-US markets. This strategy will remain the cornerstone of our work on our LaNeo MDMA product as we continue to establish ourselves as the first choice for clinical trial practitioners and prescriber suppliers.”
Irrevocability of Cortexa Joint Venture
PharmAla is furthermore gratified that the Board of Cortexa has seen fit to vote that PharmAla has completed all precedents relating to the transfer of intellectual property to Cortexa, and as such the Joint Venture is now permanent and irrevocable.
Publication of Patent for APA-001
PharmAla is pleased that the US Patent and Trademark Office (USPTO) has issued patent 12042478, supporting PharmAla’s APA-001 composition of matter for (R)-2-[(2H- 1,3-Benzodioxol-5-YL)Methyl]Pyrrolidine. PharmAla continues to believe based on preclinical studies that this molecule may have suitability and applicability as a treatment in a range of indications. It exhibits pro-social effects at lower doses than MDMA, in addition to acting on the 5HT1A receptor (similar to molecules approved to treat Anxiety and Depression), and is believed to trigger neuroplasticity via binding to intracellular 5HT2A receptors.
“We continue to progress our work towards the understanding and applicability of APA-01. As a 5HT1a agonist, the potential of this molecule extends to indications beyond those where MDMA can be used,” said Harpreet Kaur, Vice President of Research, PharmAla Biotech.
PharmAla expresses its gratitude to IPON, which has continued to support efforts to secure global patents for molecules like APA-01 with over $160,000 in non-dilutive grant proposals accepted by PharmAla in 2024. With support from IPON, PharmAla has filed patents to secure its made-in-canada intellectual property in a large number of globally relevant jurisdictions.
CEO Contract and RSU Grant
PharmAla’s Board of Directors has voted to approve a new contract for PharmAla’s CEO, Nicholas Kadysh. The CEO’s salary shall be $170,000 per annum, with a further annual bonus of up to 50%, which may be granted at the discretion of the Board of Directors. The CEO’s salary shall be reviewed annually by the Compensation Committee of the Board of Directors of PharmAla.
The Board of Directors of PharmAla has also granted the CEO, Nicholas Kadysh, with 2 Million Restricted Share Units (RSUs), to be vested quarterly over one year, in light of his continuing performance in the execution of the Company’s goals. All shares granted are subject to a 4 month hold.
PharmAla Biotech Holdings Inc. (CSE: MDMA) is a biotechnology company focused on the research, development, and manufacturing of MDXX class molecules, including MDMA. PharmAla was founded with a dual focus: alleviating the global backlog of generic, clinical-grade MDMA to enable clinical trials, and to develop novel drugs in the same class. PharmAla is a “regulatory first” organization, formed under the principle that true success in the psychedelics industry will only be achieved through excellent relationships with regulators. Our team of dedicated professionals includes regulatory experts, scientists, and biomanufacturing professionals. PharmAla has built what it believes to be North America’s first cGMP MDMA value chain, encompassing GMP manufacturing of Active Pharmaceutical Ingredient (API), and drug product formulation. PharmAla’s research and development unit has also begun preclinical research into two patented Novel Chemical Entities (NCEs) based on MDXX class molecules, with proof-of-concept research currently ongoing at the University of Arkansas Medical School.
Nicholas Kadysh, CEO
press@pharmala.ca